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Strain differences in the gating-disruptive effects of apomorphine: Relationship to gene expression in nucleus accumbens signaling pathways

BACKGROUND: Prepulse inhibition (PPI) of startle is a measure of sensorimotor gating that is deficient in certain psychiatric disorders, including schizophrenia. Sprague Dawley (SD) rats are more sensitive to PPI-disruptive effects of apomorphine (APO) at long inter-stimulus intervals (ISIs) (60-120...

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Bibliografische gegevens
Hoofdauteurs: Shilling, Paul D., Saint Marie, Richard L., Shoemaker, Jody M., Swerdlow, Neal R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771724/
https://ncbi.nlm.nih.gov/pubmed/18083141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2007.10.015
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