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Probing the molecular basis for an inherited sensitivity to the startle-gating disruptive effects of apomorphine in rats

BACKGROUND: Prepulse inhibition of acoustic startle (PPI) is deficient in several heritable brain disorders. In rats, the dopamine agonist, apomorphine (APO), reduces PPI and expression of the early gene, c-fos, within the nucleus accumbens (NAC) core. Both of these effects are greater in Sprague–Da...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: Swerdlow, Neal R., Breier, Michelle R., Saint Marie, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944297/
https://ncbi.nlm.nih.gov/pubmed/21365203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2228-1
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