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Opposite effects of tolcapone on amphetamine-disrupted startle gating in low vs. high COMT-expressing rat strains
BACKGROUND: Differential sensitivity to the prepulse inhibition (PPI)-disruptive effects of dopamine agonists in Sprague–Dawley (SD) vs. Long Evans (LE) rats is heritable, reflects differential activation of DA signaling, and is associated with differences in the brain expression of specific genes,...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3760336/ https://ncbi.nlm.nih.gov/pubmed/23567203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2013.03.015 |
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