Effect of Altering the tRNA [Formula: see text] Concentration in Human Immunodeficiency Virus Type 1 upon Its Annealing to Viral RNA, GagPol Incorporation, and Viral Infectivity

Human immunodeficiency virus type 1 (HIV-1) uses tRNA [Formula: see text] as a primer for reverse transcription and, during viral assembly, this tRNA is selectively packaged into the virus along with the other major tRNA(Lys), tRNA [Formula: see text]. Increasing the cytoplasmic concentration of tRN...

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Bibliographic Details
Main Authors: Gabor, Juliana, Cen, Shan, Javanbakht, Hassan, Niu, Meijuan, Kleiman, Lawrence
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC136429/
https://ncbi.nlm.nih.gov/pubmed/12186893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.18.9096-9102.2002
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