Immunogenicity and Tolerogenicity of Hepatitis B Virus Structural and Nonstructural Proteins: Implications for Immunotherapy of Persistent Viral Infections

Persistent hepatitis B virus (HBV) infection is characterized by a weak and narrowly focused CD8(+) T-cell response to HBV that is thought to reflect the induction of central and/or peripheral tolerance to HBV proteins in neonatal and adult onset infections, respectively. Immunotherapeutic strategie...

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Vydáno v:	J Virol
Hlavní autoři:	Kakimi, Kazuhiro, Isogawa, Masanori, Chung, JoSan, Sette, Alessandro, Chisari, Francis V.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2002
Témata:	Pathogenesis and Immunity
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136410/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12163580/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.17.8609-8620.2002
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