Immunogenicity and Tolerogenicity of Hepatitis B Virus Structural and Nonstructural Proteins: Implications for Immunotherapy of Persistent Viral Infections

Persistent hepatitis B virus (HBV) infection is characterized by a weak and narrowly focused CD8(+) T-cell response to HBV that is thought to reflect the induction of central and/or peripheral tolerance to HBV proteins in neonatal and adult onset infections, respectively. Immunotherapeutic strategie...

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Bibliografiset tiedot
Päätekijät: Kakimi, Kazuhiro, Isogawa, Masanori, Chung, JoSan, Sette, Alessandro, Chisari, Francis V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2002
Aiheet:
Pathogenesis and Immunity
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC136410/
https://ncbi.nlm.nih.gov/pubmed/12163580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.17.8609-8620.2002
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