Antigen dose-dependent predominance of either direct or sequential switch in IgE antibody responses.

Priming of CBA/J mice with minute doses of protein antigens (Ag) leads to high IgE antibody (Ab) titres in the immune sera of these animals. In contrast priming with large doses elicits only a marginal production of IgE Ab. In vitro restimulation of spleen cells from animals primed with large doses...

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Bibliographic Details
Main Authors: Sudowe, S, Rademaekers, A, Kölsch, E
Format: Artigo
Language:Inglês
Published: 1997
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364018/
https://ncbi.nlm.nih.gov/pubmed/9301538
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