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Different Effects of Nef-Mediated HLA Class I Down-Regulation on Human Immunodeficiency Virus Type 1-Specific CD8(+) T-Cell Cytolytic Activity and Cytokine Production

A previous study using a Nef-defective human immunodeficiency virus type 1 (HIV-1) mutant suggested that Nef-mediated down-regulation of HLA class I on the infected cell surface affects the cytolytic activity of HIV-1-specific cytotoxic T-lymphocyte (CTL) clones for HIV-1-infected primary CD4(+) T c...

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Bibliografske podrobnosti
Main Authors: Tomiyama, Hiroko, Akari, Hirofumi, Adachi, Akio, Takiguchi, Masafumi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC136399/
https://ncbi.nlm.nih.gov/pubmed/12097566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.15.7535-7543.2002
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