HLA Class I-Mediated Control of HIV-1 in the Japanese Population, in Which the Protective HLA-B*57 and HLA-B*27 Alleles Are Absent

We investigated the effect of HLA class I alleles on clinical parameters for HIV-1 disease progression in the Japanese population, where two strongly protective alleles, HLA-B*57 and HLA-B*27, are virtually nonexistent. HLA-B alleles showed a dominant role, primarily through HLA-B*67:01 and the HLA-...

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Detalhes bibliográficos
Main Authors: Naruto, Takuya, Gatanaga, Hiroyuki, Nelson, George, Sakai, Keiko, Carrington, Mary, Oka, Shinichi, Takiguchi, Masafumi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457252/
https://ncbi.nlm.nih.gov/pubmed/22811530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00689-12
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