Template Requirements for De Novo RNA Synthesis by Hepatitis C Virus Nonstructural Protein 5B Polymerase on the Viral X RNA

The hepatitis C virus (HCV)-encoded NS5B protein is an RNA-dependent RNA polymerase which plays a substantial role in viral replication. We expressed and purified the recombinant NS5B of an HCV genotype 3a from Esherichia coli, and we investigated its ability to bind to the viral RNA and its enzymat...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Kim, Meehyein, Kim, Hajeong, Cho, Seong-Pil, Min, Mi-Kyung
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136341/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12072495/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.14.6944-6956.2002
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