Template Requirements for De Novo RNA Synthesis by Hepatitis C Virus Nonstructural Protein 5B Polymerase on the Viral X RNA

The hepatitis C virus (HCV)-encoded NS5B protein is an RNA-dependent RNA polymerase which plays a substantial role in viral replication. We expressed and purified the recombinant NS5B of an HCV genotype 3a from Esherichia coli, and we investigated its ability to bind to the viral RNA and its enzymat...

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Argitaratua izan da:	J Virol
Egile Nagusiak:	Kim, Meehyein, Kim, Hajeong, Cho, Seong-Pil, Min, Mi-Kyung
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 2002
Gaiak:	Replication
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136341/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12072495/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.14.6944-6956.2002
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