Genetic Evidence that Interhelical Packing Interactions in the gp41 Core Are Critical for Transition of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein to the Fusion-Active State

The envelope glycoprotein complex (gp120-gp41) of human immunodeficiency virus type 1 (HIV-1) promotes the fusion of viral and cellular membranes through formation of the fusion-active six-helix bundle in the gp41 ectodomain. This gp41 core structure consists of three C-terminal helices packed in an...

Полное описание

Библиографические подробности

Опубликовано в::	J Virol
Главные авторы:	Follis, Kathryn E., Larson, Scott J., Lu, Min, Nunberg, Jack H.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2002
Предметы:	Virus-Cell Interactions
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136323/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12072535/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.14.7356-7362.2002
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!