The Mannose-Dependent Epitope for Neutralizing Antibody 2G12 on Human Immunodeficiency Virus Type 1 Glycoprotein gp120

We have analyzed the unique epitope for the broadly neutralizing human monoclonal antibody (MAb) 2G12 on the gp120 surface glycoprotein of human immunodeficiency virus type 1 (HIV-1). Sequence analysis, focusing on the conservation of relevant residues across multiple HIV-1 isolates, refined the epi...

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Detalhes bibliográficos
Main Authors: Sanders, Rogier W., Venturi, Miro, Schiffner, Linnea, Kalyanaraman, Roopa, Katinger, Hermann, Lloyd, Kenneth O., Kwong, Peter D., Moore, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136300/
https://ncbi.nlm.nih.gov/pubmed/12072528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.14.7293-7305.2002
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