Functional Evaluation of DC-SIGN Monoclonal Antibodies Reveals DC-SIGN Interactions with ICAM-3 Do Not Promote Human Immunodeficiency Virus Type 1 Transmission

DC-SIGN, a type II membrane-spanning C-type lectin that is expressed on the surface of dendritic cells (DC), captures and promotes human and simian immunodeficiency virus (HIV and SIV) infection of CD4(+) T cells in trans. To better understand the mechanism of DC-SIGN-mediated virus transmission, we...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Wu, Li, Martin, Thomas D., Vazeux, Rosemay, Unutmaz, Derya, KewalRamani, Vineet N.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2002
Schlagworte:	Virus-Cell Interactions
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136240/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12021323/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.12.5905-5914.2002
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