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Functional Evaluation of DC-SIGN Monoclonal Antibodies Reveals DC-SIGN Interactions with ICAM-3 Do Not Promote Human Immunodeficiency Virus Type 1 Transmission
DC-SIGN, a type II membrane-spanning C-type lectin that is expressed on the surface of dendritic cells (DC), captures and promotes human and simian immunodeficiency virus (HIV and SIV) infection of CD4(+) T cells in trans. To better understand the mechanism of DC-SIGN-mediated virus transmission, we...
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Hlavní autoři: | , , , , |
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Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
American Society for Microbiology
2002
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC136240/ https://ncbi.nlm.nih.gov/pubmed/12021323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.12.5905-5914.2002 |
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