Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN

Here, we describe the isolation and characterization of the rhesus macaque homolog for human DC-SIGN, a dendritic cell-specific C-type lectin. mac-DC-SIGN is 92% identical to hu-DC-SIGN. mac-DC-SIGN preserves the virus transmission function of hu-DC-SIGN, capturing and efficiently transducing simian...

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Detalles Bibliográficos
Autores principales: Wu, Li, Bashirova, Arman A., Martin, Thomas D., Villamide, Loreley, Mehlhop, Erin, Chertov, Andrei O., Unutmaz, Derya, Pope, Melissa, Carrington, Mary, KewalRamani, Vineet N.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2002
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC122231/
https://ncbi.nlm.nih.gov/pubmed/11818554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032654399
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