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Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN

Here, we describe the isolation and characterization of the rhesus macaque homolog for human DC-SIGN, a dendritic cell-specific C-type lectin. mac-DC-SIGN is 92% identical to hu-DC-SIGN. mac-DC-SIGN preserves the virus transmission function of hu-DC-SIGN, capturing and efficiently transducing simian...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Wu, Li, Bashirova, Arman A., Martin, Thomas D., Villamide, Loreley, Mehlhop, Erin, Chertov, Andrei O., Unutmaz, Derya, Pope, Melissa, Carrington, Mary, KewalRamani, Vineet N.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122231/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11818554/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.032654399
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