C-Type Lectins DC-SIGN and L-SIGN Mediate Cellular Entry by Ebola Virus in cis and in trans

Ebola virus is a highly lethal pathogen responsible for several outbreaks of hemorrhagic fever. Here we show that the primate lentiviral binding C-type lectins DC-SIGN and L-SIGN act as cofactors for cellular entry by Ebola virus. Furthermore, DC-SIGN on the surface of dendritic cells is able to fun...

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Bibliographic Details
Main Authors: Alvarez, Carmen P., Lasala, Fátima, Carrillo, Jaime, Muñiz, Oscar, Corbí, Angel L., Delgado, Rafael
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC136246/
https://ncbi.nlm.nih.gov/pubmed/12050398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.13.6841-6844.2002
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