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L1 integration in a transgenic mouse model

To study integration of the human LINE-1 retrotransposon (L1) in vivo, we developed a transgenic mouse model of L1 retrotransposition that displays de novo somatic L1 insertions at a high frequency, occasionally several insertions per mouse. We mapped 3′ integration sites of 51 insertions by Thermal...

詳細記述

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書誌詳細
主要な著者: Babushok, Daria V., Ostertag, Eric M., Courtney, Christine E., Choi, Janice M., Kazazian, Haig H.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1361720/
https://ncbi.nlm.nih.gov/pubmed/16365384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.4571606
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