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L1 retrotransposition occurs mainly in embryogenesis and creates somatic mosaicism
Long Interspersed Element 1 (L1) is a retrotransposon that comprises ∼17% of the human genome. Despite its abundance in mammalian genomes, relatively little is understood about L1 retrotransposition in vivo. To study the timing and tissue specificity of retrotransposition, we created transgenic mous...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2009
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701581/ https://ncbi.nlm.nih.gov/pubmed/19487571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1803909 |
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