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Physiological and Pathological Changes in Glucose Regulate Brain Akt and Glycogen Synthase Kinase-3
Insulin regulates the phosphorylation and activities of Akt and glycogen synthase kinase-3 (GSK3) in peripheral tissues, but in the brain it is less clear how this signaling pathway is regulated in vivo and whether it is affected by diabetes. We found that Akt and GSK3 are sensitive to glucose, beca...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1361688/ https://ncbi.nlm.nih.gov/pubmed/16179343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M508824200 |
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