Direct, activating interaction between glycogen synthase kinase-3β and p53 after DNA damage

Glycogen synthase kinase-3β (GSK3β) is a central figure in Wnt signaling, in which its activity is controlled by regulatory binding proteins. Here we show that binding proteins outside the Wnt pathway also control the activity of GSK3β. DNA damage induced by camptothecin, which activates the tumor s...

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Detalhes bibliográficos
Main Authors: Watcharasit, Piyajit, Bijur, Gautam N., Zmijewski, Jaroslaw W., Song, Ling, Zmijewska, Anna, Chen, Xinbin, Johnson, Gail V. W., Jope, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123001/
https://ncbi.nlm.nih.gov/pubmed/12048243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122062299
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