Direct, activating interaction between glycogen synthase kinase-3β and p53 after DNA damage

Glycogen synthase kinase-3β (GSK3β) is a central figure in Wnt signaling, in which its activity is controlled by regulatory binding proteins. Here we show that binding proteins outside the Wnt pathway also control the activity of GSK3β. DNA damage induced by camptothecin, which activates the tumor s...

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Détails bibliographiques
Auteurs principaux: Watcharasit, Piyajit, Bijur, Gautam N., Zmijewski, Jaroslaw W., Song, Ling, Zmijewska, Anna, Chen, Xinbin, Johnson, Gail V. W., Jope, Richard S.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2002
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC123001/
https://ncbi.nlm.nih.gov/pubmed/12048243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122062299
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