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Shp-1 mediates the anti-proliferative activity of TIMP-2 in human microvascular endothelial cells

The tissue inhibitors of metalloproteinases (TIMPs) regulate matrix metalloproteinase (MMP) activity required for cell migration/invasion associated with cancer progression and angiogenesis. TIMPs also modulate cell proliferation in vitro and angiogenesis in vivo independent of their MMP-inhibitory...

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Detalhes bibliográficos
Main Authors: Seo, Dong-Wan, Li, Hongmei, Qu, Cheng-Kui, Oh, Junseo, Kim, Young-Sik, Diaz, Tere, Wei, Beiyang, Han, Jeung-Whan, Stetler-Stevenson, William G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1361361/
https://ncbi.nlm.nih.gov/pubmed/16326706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M509932200
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