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TIMP1 induces CD44 expression and the activation and nuclear translocation of SHP1 during the late centrocyte/post-germinal center B cell differentiation

Tissue inhibitor of metalloproteinase-1 (TIMP1) is a survival factor of germinal center (GC) B cells, and its over-expression is correlated with aggressive B cell lymphomas and classical Hodgkin lymphomas. We previously demonstrated that TIMP1 down-regulates B-cell receptor and BCL6, and activates i...

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Detalhes bibliográficos
Main Authors: Kim, Young-Sik, Seo, Dong-Wan, Kong, Su-Kang, Lee, Ju-Han, Lee, Eung-Seok, Stetler-Stevenson, Maryalice, Stetler-Stevenson, William G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448268/
https://ncbi.nlm.nih.gov/pubmed/18502033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.04.020
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