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Simian Immunodeficiency Virus Nef Protein Delays the Progression of CD4(+) T Cells through G(1)/S Phase of the Cell Cycle

Human and simian immunodeficiency virus (HIV and SIV, respectively) infections are characterized by gradual depletion of CD4(+) T cells. The underlying mechanisms of CD4(+) T-cell depletion and HIV and SIV persistence are not fully determined. The Nef protein is expressed early in infection and is n...

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Detalhes bibliográficos
Main Authors: Ndolo, Thomas, Dhillon, Navdeep K., Nguyen, Hau, Guadalupe, Moraima, Mudryj, Maria, Dandekar, Satya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136077/
https://ncbi.nlm.nih.gov/pubmed/11907198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.8.3587-3595.2002
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