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Essential role of B-Raf in ERK activation during extraembryonic development

The kinases of the Raf family have been intensively studied as activators of the mitogen-activated protein kinase kinase/extra-cellular signal-regulated kinase (ERK) module in regulated and deregulated proliferation. Genetic evidence that Raf is required for ERK activation in vivo has been obtained...

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Detalhes bibliográficos
Main Authors: Galabova-Kovacs, Gergana, Matzen, Dana, Piazzolla, Daniela, Meissl, Katrin, Plyushch, Tatiana, Chen, Adele P., Silva, Alcino, Baccarini, Manuela
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360532/
https://ncbi.nlm.nih.gov/pubmed/16432225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507399103
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