Human Monoclonal Anti-Protective Antigen Antibody Completely Protects Rabbits and Is Synergistic with Ciprofloxacin in Protecting Mice and Guinea Pigs against Inhalation Anthrax

Prevention of inhalation anthrax requires early and extended antibiotic therapy, and therefore, alternative treatment strategies are needed. We investigated whether a human monoclonal antibody (AVP-21D9) to protective antigen (PA) would protect mice, guinea pigs, and rabbits against anthrax. Control...

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Detalhes bibliográficos
Main Authors: Peterson, Johnny W., Comer, Jason E., Noffsinger, David M., Wenglikowski, Autumn, Walberg, Kristin G., Chatuev, Bagram M., Chopra, Ashok K., Stanberry, Lawrence R., Kang, Angray S., Scholz, Wolfgang W., Sircar, Jagadish
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360364/
https://ncbi.nlm.nih.gov/pubmed/16428748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.2.1016-1024.2006
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