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Ligand Channeling within a G-protein-coupled Receptor: THE ENTRY AND EXIT OF RETINALS IN NATIVE OPSIN

Deactivation of light-activated rhodopsin (metarhodopsin II) involves, after rhodopsin kinase and arrestin interactions, the hydrolysis of the covalent bond of all-trans-retinal to the apoprotein. Although the long-lived storage form metarhodopsin III is transiently formed, all-trans-retinal is even...

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Detalhes bibliográficos
Main Authors: Schädel, Sandra A., Heck, Martin, Maretzki, Dieter, Filipek, Slawomir, Teller, David C., Palczewski, Krzysztof, Hofmann, Klaus Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360283/
https://ncbi.nlm.nih.gov/pubmed/12707280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M302115200
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