Loading...

A Single Amino Acid Substitution in the Activation Loop Defines the Decoy Characteristic of VEGFR-1/FLT-1

VEGFR-1 is a kinase-defective receptor tyrosine kinase (RTK) and negatively modulates angiogenesis by acting as a decoy receptor. The decoy characteristic of VEGFR-1 is required for normal development and angiogenesis. To date, there is no molecular explanation for this unusual characteristic of VEG...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Meyer, Rosana D., Mohammadi, Moosa, Rahimi, Nader
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360223/
https://ncbi.nlm.nih.gov/pubmed/16286478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M506454200
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!