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Apical Budding of a Recombinant Influenza A Virus Expressing a Hemagglutinin Protein with a Basolateral Localization Signal

Influenza virions bud preferentially from the apical plasma membrane of infected epithelial cells, by enveloping viral nucleocapsids located in the cytosol with its viral integral membrane proteins, i.e., hemagglutinin (HA), neuraminidase (NA), and M2 proteins, located at the plasma membrane. Becaus...

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Detalhes bibliográficos
Main Authors: Mora, Rosalia, Rodriguez-Boulan, Enrique, Palese, Peter, García-Sastre, Adolfo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136015/
https://ncbi.nlm.nih.gov/pubmed/11884578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.7.3544-3553.2002
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