Apical Budding of a Recombinant Influenza A Virus Expressing a Hemagglutinin Protein with a Basolateral Localization Signal

Influenza virions bud preferentially from the apical plasma membrane of infected epithelial cells, by enveloping viral nucleocapsids located in the cytosol with its viral integral membrane proteins, i.e., hemagglutinin (HA), neuraminidase (NA), and M2 proteins, located at the plasma membrane. Becaus...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Mora, Rosalia, Rodriguez-Boulan, Enrique, Palese, Peter, García-Sastre, Adolfo
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2002
Schlagworte:	Structure and Assembly
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136015/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11884578/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.7.3544-3553.2002
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