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Apical Budding of a Recombinant Influenza A Virus Expressing a Hemagglutinin Protein with a Basolateral Localization Signal

Influenza virions bud preferentially from the apical plasma membrane of infected epithelial cells, by enveloping viral nucleocapsids located in the cytosol with its viral integral membrane proteins, i.e., hemagglutinin (HA), neuraminidase (NA), and M2 proteins, located at the plasma membrane. Becaus...

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Bibliografiske detaljer
Main Authors: Mora, Rosalia, Rodriguez-Boulan, Enrique, Palese, Peter, García-Sastre, Adolfo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136015/
https://ncbi.nlm.nih.gov/pubmed/11884578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.7.3544-3553.2002
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