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Apical Budding of a Recombinant Influenza A Virus Expressing a Hemagglutinin Protein with a Basolateral Localization Signal

Influenza virions bud preferentially from the apical plasma membrane of infected epithelial cells, by enveloping viral nucleocapsids located in the cytosol with its viral integral membrane proteins, i.e., hemagglutinin (HA), neuraminidase (NA), and M2 proteins, located at the plasma membrane. Becaus...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Mora, Rosalia, Rodriguez-Boulan, Enrique, Palese, Peter, García-Sastre, Adolfo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2002
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136015/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11884578/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.7.3544-3553.2002
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