Mutation of the Dominant Endocytosis Motif in Human Immunodeficiency Virus Type 1 gp41 Can Complement Matrix Mutations without Increasing Env Incorporation

The human immunodeficiency virus type 1 transmembrane glycoprotein (TM) is efficiently endocytosed in a clathrin-dependent manner. Internalization is mediated by a tyrosine-containing motif within the cytoplasmic domain, and replacement of the cytoplasmic tyrosine by cysteine or phenylalanine increa...

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Veröffentlicht in:	J Virol
Hauptverfasser:	West, John T., Weldon, Sally K., Wyss, Stephanie, Lin, Xiaoxu, Yu, Qin, Thali, Markus, Hunter, Eric
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2002
Schlagworte:	Replication
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136014/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11884559/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.7.3338-3349.2002
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