Mutation of the Dominant Endocytosis Motif in Human Immunodeficiency Virus Type 1 gp41 Can Complement Matrix Mutations without Increasing Env Incorporation

The human immunodeficiency virus type 1 transmembrane glycoprotein (TM) is efficiently endocytosed in a clathrin-dependent manner. Internalization is mediated by a tyrosine-containing motif within the cytoplasmic domain, and replacement of the cytoplasmic tyrosine by cysteine or phenylalanine increa...

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Detalhes bibliográficos
Main Authors: West, John T., Weldon, Sally K., Wyss, Stephanie, Lin, Xiaoxu, Yu, Qin, Thali, Markus, Hunter, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136014/
https://ncbi.nlm.nih.gov/pubmed/11884559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.7.3338-3349.2002
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