Human Immunodeficiency Virus Type 1 Nef Binds to Tumor Suppressor p53 and Protects Cells against p53-Mediated Apoptosis

The nef gene product of human immunodeficiency virus type 1 (HIV-1) is important for the induction of AIDS, and key to its function is its ability to manipulate T-cell function by targeting cellular signal transduction proteins. We reported that Nef coprecipitates a multiprotein complex from cells w...

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Autores principales: Greenway, Alison L., McPhee, Dale A., Allen, Kelly, Johnstone, Ricky, Holloway, Gavan, Mills, John, Azad, Ahmed, Sankovich, Sonia, Lambert, Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC135999/
https://ncbi.nlm.nih.gov/pubmed/11861836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.6.2692-2702.2002
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