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Diminished Production of Human Immunodeficiency Virus Type 1 in Astrocytes Results from Inefficient Translation of gag, env, and nef mRNAs despite Efficient Expression of Tat and Rev

Astrocytes infected with human immunodeficiency virus type 1 (HIV-1) produce only minimal quantities of virus. The molecular events that limit acute-phase HIV-1 infection of astrocytes were examined after inducing acute-phase replication by transfection with the pNL4-3 proviral plasmid. The levels o...

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Detalhes bibliográficos
Main Authors: Gorry, Paul R., Howard, Jane L., Churchill, Melissa J., Anderson, Jenny L., Cunningham, Anthony, Adrian, Deborah, McPhee, Dale A., Purcell, Damian F. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC103840/
https://ncbi.nlm.nih.gov/pubmed/9847339
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