Identification of Temperature-Sensitive Mutations in the Phosphoprotein of Respiratory Syncytial Virus That Are Likely Involved in Its Interaction with the Nucleoprotein

The phosphoprotein (P) of human respiratory syncytial virus (RSV) is an essential component of the viral RNA polymerase, along with the large polymerase (L), nucleocapsid (N), and M2-1 proteins. By screening a randomly mutagenized P gene cDNA library, two independent mutations, one with a substituti...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Lu, Bin, Brazas, Robert, Ma, Chien-Hui, Kristoff, Tina, Cheng, Xing, Jin, Hong
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135989/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11861854/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.6.2871-2880.2002
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