Identification of Temperature-Sensitive Mutations in the Phosphoprotein of Respiratory Syncytial Virus That Are Likely Involved in Its Interaction with the Nucleoprotein

The phosphoprotein (P) of human respiratory syncytial virus (RSV) is an essential component of the viral RNA polymerase, along with the large polymerase (L), nucleocapsid (N), and M2-1 proteins. By screening a randomly mutagenized P gene cDNA library, two independent mutations, one with a substituti...

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Pubblicato in:	J Virol
Autori principali:	Lu, Bin, Brazas, Robert, Ma, Chien-Hui, Kristoff, Tina, Cheng, Xing, Jin, Hong
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Replication
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135989/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11861854/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.6.2871-2880.2002
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