Identification of Temperature-Sensitive Mutations in the Phosphoprotein of Respiratory Syncytial Virus That Are Likely Involved in Its Interaction with the Nucleoprotein

The phosphoprotein (P) of human respiratory syncytial virus (RSV) is an essential component of the viral RNA polymerase, along with the large polymerase (L), nucleocapsid (N), and M2-1 proteins. By screening a randomly mutagenized P gene cDNA library, two independent mutations, one with a substituti...

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में प्रकाशित:	J Virol
मुख्य लेखकों:	Lu, Bin, Brazas, Robert, Ma, Chien-Hui, Kristoff, Tina, Cheng, Xing, Jin, Hong
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	American Society for Microbiology (ASM) 2002
विषय:	Replication
ऑनलाइन पहुंच:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135989/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11861854/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.6.2871-2880.2002
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