Interaction of the CC-Chemokine RANTES with Glycosaminoglycans Activates a p44/p42 Mitogen-Activated Protein Kinase-Dependent Signaling Pathway and Enhances Human Immunodeficiency Virus Type 1 Infectivity

The interaction of the CC-chemokine RANTES with its cell surface receptors transduces multiple intracellular signals: low concentrations of RANTES (1 to 10 nM) stimulate G-protein-coupled receptor (GPCR) activity, and higher concentrations (1 μM) activate a phosphotyrosine kinase (PTK)-dependent pat...

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Autores principales: Chang, Theresa Li-Yun, Gordon, Cynthia J., Roscic-Mrkic, Branka, Power, Christine, Proudfoot, Amanda E. I., Moore, John P., Trkola, Alexandra
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC135942/
https://ncbi.nlm.nih.gov/pubmed/11836402
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