CC-Chemokine Ligand 2 (CCL2) Suppresses High Density Lipoprotein (HDL) Internalization and Cholesterol Efflux via CC-Chemokine Receptor 2 (CCR2) Induction and p42/44 Mitogen-activated Protein Kinase (MAPK) Activation in Human Endothelial Cells

High density lipoprotein (HDL) has been proposed to be internalized and to promote reverse cholesterol transport in endothelial cells (ECs). However, the mechanism underlying these processes has not been studied. In this study, we aim to characterize HDL internalization and cholesterol efflux in ECs...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Sun, Run-Lu, Huang, Can-Xia, Bao, Jin-Lan, Jiang, Jie-Yu, Zhang, Bo, Zhou, Shu-Xian, Cai, Wei-Bin, Wang, Hong, Wang, Jing-Feng, Zhang, Yu-Ling
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Lipids
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016689/
https://ncbi.nlm.nih.gov/pubmed/27458015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.714279
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