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CC-Chemokine Ligand 2 (CCL2) Suppresses High Density Lipoprotein (HDL) Internalization and Cholesterol Efflux via CC-Chemokine Receptor 2 (CCR2) Induction and p42/44 Mitogen-activated Protein Kinase (MAPK) Activation in Human Endothelial Cells

High density lipoprotein (HDL) has been proposed to be internalized and to promote reverse cholesterol transport in endothelial cells (ECs). However, the mechanism underlying these processes has not been studied. In this study, we aim to characterize HDL internalization and cholesterol efflux in ECs...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sun, Run-Lu, Huang, Can-Xia, Bao, Jin-Lan, Jiang, Jie-Yu, Zhang, Bo, Zhou, Shu-Xian, Cai, Wei-Bin, Wang, Hong, Wang, Jing-Feng, Zhang, Yu-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016689/
https://ncbi.nlm.nih.gov/pubmed/27458015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.714279
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