The CC-Chemokine RANTES Increases the Attachment of Human Immunodeficiency Virus Type 1 to Target Cells via Glycosaminoglycans and Also Activates a Signal Transduction Pathway That Enhances Viral Infectivity

We have studied the mechanisms by which the CC-chemokine RANTES can enhance the infectivities of human immunodeficiency virus type 1 (HIV-1) and other enveloped viruses, when present at concentrations in excess of 500 ng/ml in vitro. Understanding the underlying mechanisms might throw light on funda...

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Detalhes bibliográficos
Main Authors: Trkola, Alexandra, Gordon, Cynthia, Matthews, Jamie, Maxwell, Elizabeth, Ketas, Tom, Czaplewski, Lloyd, Proudfoot, Amanda E. I., Moore, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112716/
https://ncbi.nlm.nih.gov/pubmed/10400729
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