A Replication-Competent, Neutralization-Sensitive Variant of Simian Immunodeficiency Virus Lacking 100 Amino Acids of Envelope

Coding sequences for the first two variable loops of the gp120 envelope glycoprotein were removed from simian immunodeficiency virus (SIV) strain 239 (SIVmac239). This deletion encompassed 100 amino acids. The resulting virus replicated poorly after transfection into immortalized T-cell lines, with...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Johnson, Welkin E., Morgan, Jennifer, Reitter, Julie, Puffer, Bridget A., Czajak, Susan, Doms, Robert W., Desrosiers, Ronald C.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2002
Fag:	Replication
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135934/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11836385/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.76.5.2075-2086.2002
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