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Early- and Intermediate-Stage Variants of Simian Immunodeficiency Virus Replicate Efficiently in Cells Lacking CCR5

Primate lentiviruses are thought to use the chemokine receptor CCR5 as the major coreceptor for entry into cells. Here we show that some variants of simian immunodeficiency virus (SIV) replicate efficiently in peripheral blood mononuclear cells (PBMCs) lacking a functional CCR5. There were differenc...

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Bibliografiske detaljer
Main Authors: Forte, Serene, Harmon, Mary-Elizabeth, Pineda, Mario J., Overbaugh, Julie
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC187416/
https://ncbi.nlm.nih.gov/pubmed/12915585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.17.9723-9727.2003
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