A Replication-Competent, Neutralization-Sensitive Variant of Simian Immunodeficiency Virus Lacking 100 Amino Acids of Envelope

Coding sequences for the first two variable loops of the gp120 envelope glycoprotein were removed from simian immunodeficiency virus (SIV) strain 239 (SIVmac239). This deletion encompassed 100 amino acids. The resulting virus replicated poorly after transfection into immortalized T-cell lines, with...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Johnson, Welkin E., Morgan, Jennifer, Reitter, Julie, Puffer, Bridget A., Czajak, Susan, Doms, Robert W., Desrosiers, Ronald C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Replication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC135934/
https://ncbi.nlm.nih.gov/pubmed/11836385
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi