Differential Activation of Influenza A Virus Endonuclease Activity Is Dependent on Multiple Sequence Differences between the Virion RNA and cRNA Promoters

Influenza virus endonuclease activity was studied in vitro with model virion RNA (vRNA) and cRNA molecules. We show that endonuclease activity can be partially rescued by transplanting vRNA-like promoter features into the model cRNA promoter. This study defines three distinctive features within the...

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Argitaratua izan da:	J Virol
Egile Nagusiak:	Leahy, Michael B., Zecchin, Giuseppe, Brownlee, George G.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 2002
Gaiak:	Replication
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135883/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11799200/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.4.2019-2023.2002
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