Differential Activation of Influenza A Virus Endonuclease Activity Is Dependent on Multiple Sequence Differences between the Virion RNA and cRNA Promoters

Influenza virus endonuclease activity was studied in vitro with model virion RNA (vRNA) and cRNA molecules. We show that endonuclease activity can be partially rescued by transplanting vRNA-like promoter features into the model cRNA promoter. This study defines three distinctive features within the...

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Bibliografiska uppgifter
Huvudupphovsmän: Leahy, Michael B., Zecchin, Giuseppe, Brownlee, George G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2002
Ämnen:
Replication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC135883/
https://ncbi.nlm.nih.gov/pubmed/11799200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.4.2019-2023.2002
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