Differential Activation of Influenza A Virus Endonuclease Activity Is Dependent on Multiple Sequence Differences between the Virion RNA and cRNA Promoters

Influenza virus endonuclease activity was studied in vitro with model virion RNA (vRNA) and cRNA molecules. We show that endonuclease activity can be partially rescued by transplanting vRNA-like promoter features into the model cRNA promoter. This study defines three distinctive features within the...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Leahy, Michael B., Zecchin, Giuseppe, Brownlee, George G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135883/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11799200/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.4.2019-2023.2002
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