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Differential Activation of Influenza A Virus Endonuclease Activity Is Dependent on Multiple Sequence Differences between the Virion RNA and cRNA Promoters

Influenza virus endonuclease activity was studied in vitro with model virion RNA (vRNA) and cRNA molecules. We show that endonuclease activity can be partially rescued by transplanting vRNA-like promoter features into the model cRNA promoter. This study defines three distinctive features within the...

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Библиографические подробности
Главные авторы: Leahy, Michael B., Zecchin, Giuseppe, Brownlee, George G.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2002
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC135883/
https://ncbi.nlm.nih.gov/pubmed/11799200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.4.2019-2023.2002
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