Kaposi's Sarcoma-Associated Herpesvirus-Encoded G Protein-Coupled Receptor ORF74 Constitutively Activates p44/p42 MAPK and Akt via G(i) and Phospholipase C-Dependent Signaling Pathways

The G protein-coupled receptor encoded by Kaposi's sarcoma-associated herpesvirus, also referred to as ORF74, has been shown to stimulate oncogenic and angiogenic signaling pathways in a constitutively active manner. The biochemical routes linking ORF74 to these signaling pathways are poorly defined...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Smit, Martine J., Verzijl, Dennis, Casarosa, Paola, Navis, Marjon, Timmerman, Henk, Leurs, Rob
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2002
Assuntos:	Virus-Cell Interactions
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135879/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11799169/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.4.1744-1752.2002
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