Activation of NF-κB by the Human Herpesvirus 8 Chemokine Receptor ORF74: Evidence for a Paracrine Model of Kaposi's Sarcoma Pathogenesis

Infection with human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma (KS)-associated herpesvirus, is necessary for the development of KS. The HHV-8 lytic-phase gene ORF74 is related to G protein-coupled receptors, particularly interleukin-8 (IL-8) receptors. ORF74 activates the inositol p...

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Detalhes bibliográficos
Main Authors: Pati, Shibani, Cavrois, Marielle, Guo, Hong-Guang, Foulke, James S., Kim, Jynho, Feldman, Ricardo A., Reitz, Marvin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115111/
https://ncbi.nlm.nih.gov/pubmed/11507211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.18.8660-8673.2001
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