A Gene Capable of Blocking Apoptosis Can Substitute for the Herpes Simplex Virus Type 1 Latency-Associated Transcript Gene and Restore Wild-Type Reactivation Levels

After ocular herpes simplex virus type 1 (HSV-1) infection, the virus travels up axons and establishes a lifelong latent infection in neurons of the trigeminal ganglia. LAT (latency-associated transcript), the only known viral gene abundantly transcribed during HSV-1 neuronal latency, is required fo...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Perng, Guey-Chuen, Maguen, Barak, Jin, Ling, Mott, Kevin R., Osorio, Nelson, Slanina, Susan M., Yukht, Ada, Ghiasi, Homayon, Nesburn, Anthony B., Inman, Melissa, Henderson, Gail, Jones, Clinton, Wechsler, Steven L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135864/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11773398/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.3.1224-1235.2002
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!