Synthesis and evaluation of phosphorescent oligonucleotide probes for hybridisation assays

Monofunctional, p-isothiocyanatophenyl-derivatives of platinum (II)-coproporphyrin-I (PtCP-NCS) were evaluated as phosphorescent labelling reagents for synthetic oligonucleotides containing a 3′- or 5′-amino modification. Synthesis and purification conditions were optimised to generate high yields a...

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Bibliographic Details
Main Authors: O’Sullivan, Paul J., Burke, Martina, Soini, Aleksi E., Papkovsky, Dmitri B.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2002
Subjects:
NAR Methods Online
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC135836/
https://ncbi.nlm.nih.gov/pubmed/12409473
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