A High-Capacity, Capsid-Modified Hybrid Adenovirus/Adeno-Associated Virus Vector for Stable Transduction of Human Hematopoietic Cells

To achieve stable gene transfer into human hematopoietic cells, we constructed a new vector, ΔAd5/35.AAV. This vector has a chimeric capsid containing adenovirus type 35 fibers, which conferred efficient infection of human hematopoietic cells. The ΔAd5/35.AAV vector genome is deleted for all viral g...

Descripción completa

Detalles Bibliográficos

Publicado en:	J Virol
Autores principales:	Shayakhmetov, Dmitry M., Carlson, Cheryl A., Stecher, Hartmut, Li, Qiliang, Stamatoyannopoulos, George, Lieber, André
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2002
Materias:	Gene Therapy
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135810/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11773389/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.3.1135-1143.2002
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!