A High-Capacity, Capsid-Modified Hybrid Adenovirus/Adeno-Associated Virus Vector for Stable Transduction of Human Hematopoietic Cells

To achieve stable gene transfer into human hematopoietic cells, we constructed a new vector, ΔAd5/35.AAV. This vector has a chimeric capsid containing adenovirus type 35 fibers, which conferred efficient infection of human hematopoietic cells. The ΔAd5/35.AAV vector genome is deleted for all viral g...

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Dades bibliogràfiques

Publicat a:	J Virol
Autors principals:	Shayakhmetov, Dmitry M., Carlson, Cheryl A., Stecher, Hartmut, Li, Qiliang, Stamatoyannopoulos, George, Lieber, André
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2002
Matèries:	Gene Therapy
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135810/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11773389/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.3.1135-1143.2002
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